Vault 101

Alphonse Almodovar became the new overseer of Vault 101 sometime before 2258. Under his rule, the Vault changed into a police state with a strict policy of isolationism. Early in Alphonse's tenure as overseer around 2258-2259, James and his child, later known as the Lone Wanderer, came to the Vault seeking shelter and arrived in front of Vault 101. James proposed to become Vault 101's new physician in return for entry into Vault 101, and Alphonse granted his request. James kept his child ignorant of their origins because of his agreement with Alphonse, convincing the Lone Wanderer that they were born in the Vault. This is set three years before James leaves the Vault and you have to go after him.