Royal Air Force pilot Captain Kate Sinclair, who crashes in Afghanistan and stumbles upon a hidden Soviet bunker. Seeking refuge inside, Kate accidentally awakens terrifying bio-engineered creatures created during the Cold War. These monstrous beings, a mix of human and alien DNA, are highly aggressive and nearly unstoppable. After barely escaping, Kate finds a nearby U.S. military base, where she warns the soldiers about the deadly creatures lurking in the bunker. Together, they prepare for a brutal fight to survive as the creatures break free and attack.

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