Sherlock Holmes, created by Sir Arthur Conan Doyle, is a world-renowned fictional private detective based in London. Known for his masterful deduction, logical reasoning, and forensic science skills, Holmes demonstrates acute observational abilities and is able to deduce a person's history from the smallest details. He has a quick wit, is often sarcastic, and prefers the company of his intellect to that of society's niceties. Holmes' closest friend and companion is Dr. John Watson, whose military background provides balance to Holmes' reclusive nature. He frequently comes into conflict with the criminal mastermind Professor Moriarty, who is considered his arch-enemy. Holmes is also known to take cocaine in absence of more compelling intellectual challenges.